Standard: API 37-31151

A THIRTEEN WEEK INHALATION TOXICITY STUDY OF COMMERCIAL HEXANE IN THE RAT AND MOUSE

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Scope:

INTRODUCTION:

This study, conducted for the American Petroleum Institute, was designed to assess the toxicity of commercial hexane when administered by whole-body inhalation as a respirable vapor to 60 Fischer 344 rats (IO/sex/group) and 60 B6C3Fl mice (la/sex/group). Twenty rats (la/sex/group) and 20 mice (la/sex/group) were exposed to room air and nitrogen. The test substance was administered for 6 hours per day, 5 days per week, for 13 weeks at target concentrations of 0, 900, 3,000 and 9,000 parts per million (ppm). Exposures commenced in staggered groups by species beginning on 10 April 1989 for the rats and 11 April 1989 for the mice, and were completed on 12 July 1989 for the rats and 13 July 1989 for the mice.

Organization: American Petroleum Institute
Document Number: api 37-31151
Publish Date: 1990-01-01
Page Count: 89
Available Languages: EN
DOD Adopted: NO
ANSI Approved: NO
Most Recent Revision: YES
Current Version: NO
Status: Inactive
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