scope:

Preface to the Second Edition

The second edition incorporates the new (2008) WHO classification of hematopoietic tumors. All chapters have been significantly expanded including an added chapter on the immunophenotypic features during normal differentiation of hematopoietic cells and much more detailed discussion on the role of flow cytometry in the diagnosis of myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria. The number of color illustrations has been increased to better describe the immunophenotypic features of different neoplasms with emphasis on typical immunophenotypic features, differential diagnosis, unusual pattern, and overlapping phenotypic features between different entities. The phenotypic criteria and statistical data on monocytic proliferations, acute promyelocytic leukemia, and T-cell disorders were upgraded to reflect significant number of new cases. Similar to the first edition, flow cytometry data were correlated with morphology, immunohistochemistry, and chromosomal/molecular characteristics.