CRC - DKE2865
Drug Metabolizing Enzymes : Cytochrome P450 and Other Enzymes in Drug Discovery and Development
| Organization: | CRC |
| Publication Date: | 3 September 2003 |
| Status: | active |
| Page Count: | 609 |
scope:
Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.
Document History