NEN-EN 16418
Paper and board - Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)
active, Most Current
| Organization: | NEN |
| Publication Date: | 1 April 2014 |
| Status: | active |
| Page Count: | 24 |
| ICS Code (Paper and board): | 85.060 |
scope:
NEN-EN 16418 specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board food contact materials using specifically the HepG2 cell line. Compared to the EN 15845, HepG2 cells are more representative of a human oral exposure to xenobiotics, due to the presence in the cells of phase I, II and III enzymes of the metabolism.
Document History
NEN-EN 16418
April 1, 2014
Paper and board - Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)
NEN-EN 16418 specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board food contact materials using specifically the HepG2 cell line. Compared to the...
May 1, 2012
Paper and board - Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)
NEN-EN 16418 specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board food contact materials using specifically the HepG2 cell line. Compared to the...