scope:

This Report deals first with biological considerations that inform the rational use of radionuclide dosimetry. Radiobiological factors in the selection of radionuclides and tumour and normal-tissue doseâ€"responses are discussed. Then, the MIRD (medical internal radiation dose) approach to nuclear medical dosimetry, a robust method that has proven its clinical utility, is described. Following on is an elaboration of non-uniform distri-butions of radioactivity and of varying dose rates. Lastly, the Report deals with techniques and procedures for measuring time variant activity distributions, image fusion, patient specific dose computations, small-scale dosimetry, and the comparison of calculated and measured doses.