API PUBL 33-32800
MUTAGENICITY OF API 83-15 HEAVY NAPHTHENIC DISTILLATE (CAS 64742-52-5) IN A MOUSE LYMPHOMA MUTATION ASSAY
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| Organization: | API |
| Publication Date: | 1 October 1986 |
| Status: | inactive |
| Page Count: | 25 |
scope:
OBJECTIVE:
The mouse lymphoma forward mutation assay evaluates a test
article's mutagenic potential in a specific locus mutation assay
using mammalian cells. The objective of the assay is to determine
the ability of a test article to induce forward mutations at the
thymidine kinase (TK) locus as assayed by colony growth of L5178Y
TK+/- mouse lymphoma cells in the presence of 5-trifluorothymidine
Document History
API PUBL 33-32800
October 1, 1986
MUTAGENICITY OF API 83-15 HEAVY NAPHTHENIC DISTILLATE (CAS 64742-52-5) IN A MOUSE LYMPHOMA MUTATION ASSAY
OBJECTIVE:
The mouse lymphoma forward mutation assay evaluates a test article's mutagenic potential in a specific locus mutation assay using mammalian cells. The objective of the assay is to...