API PUBL 33-31224
MUTAGENICITY IN A MOUSE LYMPHOMA MUTATION ASSAY API 81-10 HYDRODESULFURIZED MIDDLE DISTILLATE CAS 64742-80-9
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| Organization: | API |
| Publication Date: | 1 April 1986 |
| Status: | inactive |
| Page Count: | 27 |
scope:
OBJECTIVE:
The mouse lymphoma forward mutation assay evaluates a test
article's mutagenic potential in a specific locus mutation assay
using mammalian cells. The objective of the assay is to determine
the ability of a test article to induce forward mutations at the
thymidine kinase (TK) locus as assayed by colony growth of L5178Y
TK+/- mouse lymphoma cells in the presence of 5-trifluorothymidine
Document History
API PUBL 33-31224
April 1, 1986
MUTAGENICITY IN A MOUSE LYMPHOMA MUTATION ASSAY API 81-10 HYDRODESULFURIZED MIDDLE DISTILLATE CAS 64742-80-9
OBJECTIVE:
The mouse lymphoma forward mutation assay evaluates a test article's mutagenic potential in a specific locus mutation assay using mammalian cells. The objective of the assay is to...