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API PUBL 34-30633

MUTAGENICITY OF API 83-20 LIGHT CATALYTIC CRACKED NAPHTHA (CAS 64741-55-5) IN A MOUSE LYMPHOMA MUTATION ASSAY

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Organization: API
Publication Date: 1 February 1987
Status: inactive
Page Count: 27
scope:

OBJECTIVE:

The mouse lymphoma forward mutation assay evaluates a test article's mutagenic potential in a specific locus mutation assay using mammalian cells. The objective of the assay is to determine the ability of a test article to induce forward mutations at the thymidine kinase (TK) locus as assayed by colony growth of L5178Y TK-/- mouse lymphoma cells in the presence of 5-trifluorothymidine (TFT).

Document History

API PUBL 34-30633
February 1, 1987
MUTAGENICITY OF API 83-20 LIGHT CATALYTIC CRACKED NAPHTHA (CAS 64741-55-5) IN A MOUSE LYMPHOMA MUTATION ASSAY
OBJECTIVE: The mouse lymphoma forward mutation assay evaluates a test article's mutagenic potential in a specific locus mutation assay using mammalian cells. The objective of the assay is to...
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