API PUBL 34-30633
MUTAGENICITY OF API 83-20 LIGHT CATALYTIC CRACKED NAPHTHA (CAS 64741-55-5) IN A MOUSE LYMPHOMA MUTATION ASSAY
| Organization: | API |
| Publication Date: | 1 February 1987 |
| Status: | inactive |
| Page Count: | 27 |
scope:
OBJECTIVE:
The mouse lymphoma forward mutation assay evaluates a test
article's mutagenic potential in a specific locus mutation assay
using mammalian cells. The objective of the assay is to determine
the ability of a test article to induce forward mutations at the
thymidine kinase (TK) locus as assayed by colony growth of L5178Y
TK-/- mouse lymphoma cells in the presence of 5-trifluorothymidine
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