scope:

Fine needle aspiration biopsy is a widely accepted technique for the initial work-up and management of a patient who presents with a superficial, palpable lesion/mass. This technique is also used for a deepseated, nonpalpable lesion/mass under radiologic guidance. This minimally invasive procedure is safe, accurate, rapid, and cost effective. Patient acceptance is high and complications are minimal. The goal of this guideline is to provide recommendations for performing the procedure and optimal collection, handling, fixation, and staining of aspiration biopsy specimens. Equipment needs and patient preparation issues are addressed. NCCLS document GP20-A2 is not, however, intended to summarize the morphologic features used for diagnosis.