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CLSI M44

Method for Antifungal Disk Diffusion Susceptibility Testing of Yeasts

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Organization: CLSI
Publication Date: 1 December 2018
Status: active
Page Count: 44
scope:

This guideline provides an established methodology for disk diffusion testing of select Candida spp. For zone diameter breakpoints, interpretive categories, and recommended QC ranges for caspofungin, micafungin, fluconazole, and voriconazole, refer to CLSI document M60.4

The method described is intended for testing select Candida spp. This method is not currently applicable to any other genera and has not been used in studies of the yeast form of dimorphic fungi (eg, Blastomyces dermatitidis or Histoplasma capsulatum). Moreover, testing of filamentous fungi (ie, moulds) is not covered in the current procedure.

The method described in this guideline must be followed exactly to obtain reproducible results. When new problems are recognized or improvements in these criteria are developed, changes will be incorporated into future editions of M44 and new breakpoint information will be distributed in periodic informational supplements (see CLSI document M604).

This guideline is intended for use by, among others, health care, academic, government, industry, or independent research organizations that perform antifungal susceptibility testing of yeasts.

Document History

CLSI M44
December 1, 2018
Method for Antifungal Disk Diffusion Susceptibility Testing of Yeasts
This guideline provides an established methodology for disk diffusion testing of select Candida spp. For zone diameter breakpoints, interpretive categories, and recommended QC ranges for caspofungin,...
August 1, 2009
Zone Diameter Interpretive Standards, Corresponding Minimal Inhibitory Concentration (MIC) Interpretive Breakpoints, and Quality Control Limits for Antifungal Disk Diffusion Susceptibility Testing of Yeasts; Third Informational Supplement
A description is not available for this item.
August 1, 2009
Method for Antifungal Disk Diffusion Susceptibility Testing of Yeasts; Approved Guideline
With a need to make antifungal susceptibility testing more readily available to the clinical laboratory, CLSI document M44-A2 provides an established methodology for disk diffusion testing of Candida...
August 1, 2009
Zone Diameter Interpretive Standards, Corresponding Minimal Inhibitory Concentration (MIC) Interpretive Breakpoints, and Quality Control Limits for Antifungal Disk Diffusion Susceptibility Testing of Yeasts; Informational Supplement
A description is not available for this item.

References

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