UNLIMITED FREE ACCESS TO THE WORLD'S BEST IDEAS

close
Already an Engineering360 user? Log in.

This is embarrasing...

An error occurred while processing the form. Please try again in a few minutes.

Customize Your Engineering360 Experience

close
Privacy Policy

This is embarrasing...

An error occurred while processing the form. Please try again in a few minutes.

ASTM International - ASTM E1163-10

Standard Test Method for Estimating Acute Oral Toxicity in Rats

inactive
Buy Now
Organization: ASTM International
Publication Date: 1 November 2010
Status: inactive
Page Count: 3
ICS Code (Other pesticides and agrochemicals): 65.100.99
significance And Use:

This test method is of principal value in minimizing the number of animals required to estimate the acute oral toxicity (LD50). It also incorporates measures of variance (95 % CI) and a slope from... View More

scope:

1.1 This test method determines the lethality (LD50 value, slope and 95% confidence interval (CI)) and signs of acute toxicity from a material using a limited number of rats. The technique used in this test method is referred to as the "Stagewise, Adaptive Dose Method." This test method is an alternative to the classical LD50 test and is applicable to both liquids and solids.

1.2 This test method is not recommended for test materials which typically produce deaths beyond 2 days postdosing.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Document History

February 1, 2019
Standard Test Method for Estimating Acute Oral Toxicity in Rats
1.1 This test method determines the lethality (LD50 value, slope and 95 % confidence interval (CI)) and signs of acute toxicity from a material using a limited number of rats. The technique used in...
February 1, 2016
Standard Test Method for Estimating Acute Oral Toxicity in Rats
5.1 This test method is of principal value in minimizing the number of animals required to estimate the acute oral toxicity (LD50). It also incorporates measures of variance (95 % CI) and a slope...
ASTM E1163-10
November 1, 2010
Standard Test Method for Estimating Acute Oral Toxicity in Rats
This test method is of principal value in minimizing the number of animals required to estimate the acute oral toxicity (LD50). It also incorporates measures of variance (95 % CI) and a slope from...
October 10, 2002
Standard Test Method for Estimating Acute Oral Toxicity in Rats
This test method is of principal value in minimizing the number of animals required to estimate the acute oral toxicity (LD50). This test method is inappropriate for materials typically producing...
October 10, 1998
Standard Test Method for Estimating Acute Oral Toxicity in Rats
1.1 This test method determines the lethality (LD50 value) and signs of acute toxicity from a material using a limited number of rats. The technique used in this test method is referred to as the...
Advertisement