UNLIMITED FREE ACCESS TO THE WORLD'S BEST IDEAS

close

CLSI H52

Fetal Red Cell Detection; Approved Guideline

inactive
Buy Now
Organization: CLSI
Publication Date: 1 December 2000
Status: inactive
Page Count: 51
scope:

This document outlines the methodologies currently available and caveats for interpretation utilized in fetal RBC counting. Included are manual microscopic screening and quantitative techniques and more automated flow cytometric and static cytometric methods. Methods to ensure clinically acceptable precision and accuracy in calibration and quality control are outlined. The KBB method is currently designated the Class B reference method in this document, due to the anticipation that flow cytometric methods based upon HbF detection by monoclonal antibodies will gain acceptance as the more appropriate reference method, due to greater accuracy. The relationship to fetal RBC counting results and therapeutic administration of RhIG in the treatment of FMH in Rho or D antigen-negative women is also provided. Although the enumeration of F cells is not the primary focus of this proposed guideline, potential methods for F-cell counting are discussed, primarily in an effort to guide the subsequent standardization of this clinically useful measurement.

Document History

March 1, 2014
Red Blood Cell Diagnostic Testing Using Flow Cytometry; Approved Guideline
This document establishes performance guidelines for applying the science of flow cytometry (FCM) to RBC diagnostic testing. It provides guidelines for: Specimen collection, handling, and storage...
March 1, 2014
Red Blood Cell Diagnostic Testing Using Flow Cytometry; Approved Guideline
This document establishes performance guidelines for applying the science of flow cytometry (FCM) to RBC diagnostic testing. It provides guidelines for: • Specimen collection, handling, and storage...
CLSI H52
December 1, 2000
Fetal Red Cell Detection; Approved Guideline
This document outlines the methodologies currently available and caveats for interpretation utilized in fetal RBC counting. Included are manual microscopic screening and quantitative techniques and...

References

Advertisement