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Clinical and Laboratory Standards Institute document M59-Epidemiological Cutoff Values for Antifungal Susceptibility Testing includes epidemiological cutoff values (ECVs) and quality control tables developed following the guidance in CLSI document M57.¹ These ECVs are valid only when they are developed in accordance with CLSI document M57¹ and when minimal inhibitory concentrations or minimal effective concentrations are generated according to the reference broth dilution methods described in CLSI documents M27² and M38.³ Users should replace previously published tables with these new tables. Changes in the tables since the previous edition appear in boldface type.

Clinical and Laboratory Standards Institute (CLSI). Epidemiological Cutoff Values for Antifungal Susceptibility Testing. 3rd ed. CLSI supplement M59 (ISBN 978-1-68440-080-5 [Print]; ISBN 978-1-68440-081-2 [Electronic]). Clinical and Laboratory Standards Institute, 950 West Valley Road, Suite 2500, Wayne, Pennsylvania 19087 USA, 2020.

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¹ CLSI. Principles and Procedures for the Development of Epidemiological Cutoff Values for Antifungal Susceptibility Testing. 1st ed. CLSI guideline M57. Wayne, PA: Clinical and Laboratory Standards Institute; 2016.

² CLSI. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts. 4th ed. CLSI standard M27. Wayne, PA: Clinical and Laboratory Standards Institute; 2017.

³ CLSI. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi. 3rd ed. CLSI standard M38. Wayne, PA: Clinical and Laboratory Standards Institute; 2017.