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ASTM International - ASTM F749-13

Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit

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Organization: ASTM International
Publication Date: 1 March 2013
Status: inactive
Page Count: 3
ICS Code (Veterinary medicine): 11.220
significance And Use:

4.1 This practice is to be used to help assess the biocompatibility of materials used in medical devices. It is an acute toxicological test designed to detect the presence of injurious leachable... View More

scope:

1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices.

1.2 The liquids injected into the rabbits are those obtained by Practice F619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

1.4 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.

Document History

February 1, 2020
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is an intracutaneous reactivity test used to assess the potential of the material under test to produce irritation following intradermal injections of extracts of the material....
ASTM F749-13
March 1, 2013
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices. 1.2 The liquids injected into the rabbits are those obtained...
October 1, 2012
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices. 1.2 The liquids injected into the rabbits are those obtained...
February 1, 2007
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices. 1.2 The liquids injected in the rabbits are those obtained by...
February 1, 2007
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
This practice is to be used to help assess the biocompatibility of materials used in medical devices. It is an acute toxicological test designed to detect the presence of injurious leachable...
February 10, 1998
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices. 1.2 The liquids injected in the rabbits are those obtained by...
February 10, 1998
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices. 1.2 The liquids injected in the rabbits are those obtained by...
February 10, 1998
Standard Practice for Evaluating Material Extracts by Intracutaneous Injection in the Rabbit
1.1 This practice is a nonspecific, acute toxicity test used to help determine the biocompatibility of materials used in medical devices. 1.2 The liquids injected in the rabbits are those obtained...
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