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ASTM International - ASTM ISO/ASTM51939-05(2013)

Standard Practice for Blood Irradiation Dosimetry

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Organization: ASTM International
Publication Date: 8 August 2013
Status: inactive
Page Count: 13
ICS Code (Transfusion, infusion and injection equipment): 11.040.20
ICS Code (Radiation measurements): 17.240
significance And Use:

4.1 The assurance that blood and blood components have been properly irradiated is of crucial importance for patient health. The irradiator operator must demonstrate by means of accurate... View More

scope:

1.1 This practice outlines irradiator installation qualification, operational qualification, performance qualification, and routine product processing dosimetric procedures to be followed in the irradiation of blood and blood components by the blood-banking community. If followed, these procedures will help to ensure that the products processed with ionizing radiation from gamma, X-radiation (bremsstrahlung), or electron sources receive absorbed doses within a predetermined range.

1.2 This practice covers dosimetry for the irradiation of blood for these types of irradiators: self-contained irradiators (free-standing irradiators) utilizing 137Cs, 60Co or X-radiation (bremsstrahlung), teletherapy units, and electron accelerators. The absorbed dose range for blood irradiation is typically 15 Gy to 50 Gy. In some jurisdictions, the absorbed dose range for blood irradiation is 25 Gy to 50 Gy.

1.3 The energy range is typically from approximately 40 keV to 5 MeV for photons, and up to 10 MeV for electrons.

1.4 This practice also covers the use of radiation-sensitive indicators for the visual and qualitative indication that the product has been irradiated.

1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and to determine the applicability or regulatory limitations prior to use.

Document History

January 1, 2016
Standard Practice for Blood Irradiation Dosimetry
4.1 Blood and blood components are irradiated to predetermined absorbed doses to inactivate viable lymphocytes to help prevent transfusion-induced graft-versus-host disease (GVHD) in certain...
ASTM ISO/ASTM51939-05(2013)
August 8, 2013
Standard Practice for Blood Irradiation Dosimetry
4.1 The assurance that blood and blood components have been properly irradiated is of crucial importance for patient health. The irradiator operator must demonstrate by means of accurate...
May 15, 2005
Standard Practice for Blood Irradiation Dosimetry
4.1 The assurance that blood and blood components have been properly irradiated is of crucial importance for patient health. The irradiator operator must demonstrate by means of accurate...
January 22, 2002
Standard Practice for Blood Irradiation Dosimetry
1.1 This practice outlines irradiator installation qualification and dosimetric procedures to be followed in the irradiation of blood and blood products by the blood-banking community. If followed,...
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