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CRC - Transcatheter Valve Therapies

Organization: CRC
Publication Date: 25 September 2009
Page Count: 282


Transcatheter Valve Therapies not only chronicle the astonishing advances that have taken place in the field but also prepares the reader in a contemporary and unique fashion for the challenging future of cardiac valve therapies. The landscape of cardiac surgery is changing and so is the field of interventional cardiology.

The idea of accessing and replacing a failing valve through the patients vasculature might have been mistakenly dismissed as being an illusionary idea, but has since become the most rapidly expanding therapy of choice in cardiovascular disease. This book is designed to meet the growing needs of the cardiologist, cardiac surgeons, anesthetists and general practitioners-all jointly working towards a better quality of life for patients with heart valve disease.

The aim of the book is to provide a comprehensive overview of transcatheter valve therapies and the necessary understanding for a successful clinical introduction at individual institutions. All aspects from the logistic needs to the clinical outcomes the new therapies are covered in an unique fashion to allow the reader a constructive approach to transcatheter therapies independent of their specialist background. The author's expertise as cardiac surgeon with an extensive interventional background, having been involved in transcatheter techniques since its beginning provide a innovative patient and enduser oriented textbook.

The scope of the book is to provide the reader with handy expertise from both the surgical and interventional experience. By inventing the trans-apical procedure for treating structural heart disease, the author joined fundamental surgical and interventional strategies that are provided to the reader in the following chapters.

In such a rapidly expanding field precise description of devices might only be of limited value. The timeless quality of this book is provided by integrating fundamental development steps leading up to the successful market introduction and clinical implementation. Providing the necessary pathways illustrated by the author's own experience results in a comprehensive resource presenting in similar fashion the past, the present, and the future of transcatheter valve therapies.

All essential topics are represented in this book written for clinicians as well as for researchers in the field of transcatheter valve therapies for structural heart disease. Following a concise chronological chapter order, epidemiologic considerations emphasize the unmet needs of patients suffering from heart valve disease and provide insights into the excepted grow of a patient population at risk. But within the exciting adoption of novel therapy care should be taken to stay unbiased and ready for further changes. Ted Feldman's expertise highlights the complementing aspects of balloon aortic valvuloplasty. As a stand-alone procedure or as part of the transcatheter valve replacement. His chapter presents many technical insights into balloon aortic valvuloplasty. Introduction of a new technology requires a multilevel approach to reach successful acceptance. Many hurdles needed to be taken and the introduction of the technology chapter provides the reader with valuable hints of how transcatheter valve therapies were implemented into the surgical practice and why the introduction of the transapical approach became a strategic technique to merge interventional and surgical advantages for a given patient's best benefits. New imaging modalities as well as outlines and necessities of the hybrid environment in the context of a team-based collaboration are conveniently summarized in the same chapter.

An essential resource is found in the section highlighting the particularities of transcatheter access. Understanding the unique and demanding aortic root anatomy provides the necessary ground for most accurate device delivery and future device development. Emerging technologies require constant improvements and the author's own step-wise development might serve as a guide for future design improvements. Innovation paired with strikingly easy technical construction can provide promising solutions to complex tasks as described in the experimental work chapter, featuring not only development steps of aortic devices but also potential solutions for transcatheter tricuspid, mitral and pulmonary valve replacement. Jack Lemmon summarizes the rigorous testing requirements for endovascular medical devices in his chapter Preclinical Valved Stent Device Testing.

The clinical overview in chapter 12 Clinical Results of Aortic Transcatheter Valve Therapies provides the most recent data of the worldwide transcatheter aortic valve experience with detailed outcomes and complications in easy accessible text and table formats.

The author's personal vision of the future on transcatheter valve therapies is outlined in the Conclusion and will prepare the reader to embark into the fascinating future of endoluminal cardiac therapies.