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ASTM International - ASTM E1482-04

Standard Test Method for Neutralization of Virucidal Agents in Virucidal Efficacy Evaluations

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Organization: ASTM International
Publication Date: 1 October 2004
Status: inactive
Page Count: 3
ICS Code (Disinfectants and antiseptics): 11.080.20
ICS Code (Chemicals for industrial and domestic disinfection purposes): 71.100.35
significance And Use:

This test method is to be used for the removal of virucidal agents from agent-virus mixtures, or from agent-neutralizer-virus mixtures, after the contact period and before the inoculation... View More

scope:

1.1 This test method covers the use, in conjunction with evaluations of the virucidal efficacy, of disinfectant solutions or pressurized disinfectant spray products intended for use on inanimate nonporous environmental surfaces or for other special applications. The test method may be employed with all viruses and host systems.

1.2 This test method should be performed only by persons trained in microbiology and virology.

1.3 This test method utilizes gel filtration technology. The effectiveness of the test method is dependent on the ratio of gel bed volume to sample size and uniformity in the preparation of columns and centrifugation conditions. The effectiveness of this test method is maximized by investigator practice and experience with gel filtration techniques.

1.4 This test method will reduce, but not necessarily eliminate, disinfectant toxicity while preserving the titer of input virus.

1.5 The values stated in SI units are to be regarded as the standard.

This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Document History

November 1, 2017
Standard Practice for Use of Gel Filtration Columns for Cytotoxicity Reduction and Neutralization
Note 1: The title was formerly Standard Test Method for Neutralization of Virucidal Agents in Virucidal Efficacy Evaluations. 1.1 This practice is intended to be used to reduce the cytotoxic level...
October 1, 2012
Standard Practice for Use of Gel Filtration Columns for Cytotoxicity Reduction and Neutralization
Note 1—The title was formerly Standard Test Method for Neutralization of Virucidal Agents in Virucidal Efficacy Evaluations. 1.1 This practice is intended to be used to reduce the cytotoxic level of...
ASTM E1482-04
October 1, 2004
Standard Test Method for Neutralization of Virucidal Agents in Virucidal Efficacy Evaluations
1.1 This test method covers the use, in conjunction with evaluations of the virucidal efficacy, of disinfectant solutions or pressurized disinfectant spray products intended for use on inanimate...
April 1, 2004
Standard Test Method for Neutralization of Virucidal Agents in Virucidal Efficacy Evaluations
1.1 This test method covers the use, in conjunction with evaluations of the virucidal efficacy, of disinfectant solutions or pressurized disinfectant spray products intended for use on inanimate...
October 10, 1998
Standard Test Method for Neutralization of Virucidal Agents in Virucidal Efficacy Evaluations
1.1 This laboratory test method is intended for use in conjunction with evaluations of the virucidal efficacy of disinfectant solutions or pressurized disinfectant spray products intended for use on...
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