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Molecular Toxicology is a concise introduction to the subject, taking the reader through the theoretical principles of toxicology followed by specific examples. In the first section, the concepts behind possible mechanisms of toxicity are described (e.g. the specific enzyme or receptor system)...
The past two decades have seen rapid development of micro-/nanotechnolog
In biological research, the amount of data available to researchers has increased so much over recent years, it is becoming increasingly difficult to understand the current state of the art without some experience and understanding of data analytics and bioinformatics. An Introduction to...
An increasing number of genetically modified organisms (GMOs) continues to be produced every day. In response to the concerns raised by the development of GMOs and their incorporation in foods and feed, guidelines and regulations to govern and control the use of GMOs and their products have been...
This guideline provides recommendations for qualitative multiplex nucleic acid assay validation and verification. This guideline focuses primarily on analytical validation, analytical verification, and QC and briefly discusses establishing clinical validation and clinical verification for these...
Microarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of...
This document gives examples of how methods of surface chemical analysis in the scope of ISO TC 201 are useful to characterize the nature of substrates used to produce biosensing devices. Successful characterization will give the opportunity for a better understanding of aspects of surface...
Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic...
Praise for the Second Edition: "… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size...
Preface Gene expression profiling using microarrays has been increasingly brought to task for the simple goal of ensuring that data from a particular tissue and a particular platform match the same tissue run on another platform in another lab. Expression arrays are becoming extremely...
A guide to state-of-the-art molecular tools for monitoring and managing the toxigenicity of cyanobacteria Runaway eutrophication and climate change has made the monitoring and management of toxigenic organisms in the world's bodies of water more urgent than ever. In order to influence public policy...
This International Standard defines terms for the detection of nucleic acid sequence of interest using DNA microarrays for detection of nucleic acid. This International Standard is applicable to all methods that use microarrays for detection of nucleic acids. This International...
Microarray Technology Through Applications provides the reader with an understanding, from an applications perspective, of the diverse range of concepts required to master the experimental and data analysis aspects of microarray technology. The first chapter is a concise introduction...
ISO 16578:2013 defines terms for the detection of nucleic acid sequence of interest using DNA microarrays for detection of nucleic acid. It specifies the verification processes and parameters for molecular biology analysis, including the detection and identification of specific nucleic acid...
Praise for the first edition: "This book provides a good introduction to R, using a clear layout and detailed, reproducible examples. An ideal tool for any new R user. A wide range of topics are covered, making the book suitable for a variety of readers, from undergraduate students to professionals...
This guideline provides recommendations for the appropriate performance, validation or verification, and interpretation of nucleic acid microarrays used primarily for cytogenetic applications to measure copy number (CN) imbalances, traditional array-based comparative genomic hybridization...
Taking an interdisciplinary approach that emphasizes the adaptability of immunochemical and related bioanalytical methods to a variety of matrices, Immunoassay and Other Bioanalytical Techniques describes the strength and the versatility of these methods in a wide range of environmental and...
Microarrays can be distinguished from each other based upon characteristics such as the nature of the probe, the solid surface support used, and the specific method used for probe addressing and/or target detection. MM22 focuses on the use of nucleic acid microarrays in microbiology...
Preface Preimplantation genetic diagnosis is currently an established option for couples at risk for producing offspring with genetic disorders. With this option, they no longer have to face prenatal diagnosis and potential termination of affected pregnancies, but may from the very onset plan...
