scope:

This document describes a method for testing the susceptibility to antifungal agents of yeasts, including Candida spp. And Cryptococcus neoformans, that cause infections. This method has not been extensively validated for the yeast forms of dimorphic fungi, such as Blastomyces dermatitidis or Histoplasma capsulatum variety capsulatum.

The subcommittee has focused on developing relevant breakpoints for available antifungal agents, ¹¹ and reference MIC ranges for microdilution testing of both established and newly introduced antifungal agents.¹² Interpretive minimal inhibitory concentration (MIC) breakpoints and MIC ranges for quality control (QC) isolates are summarized in an Informational Supplemtn¹³ to this document.